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murine knockout styles. cTnT-knockout causes sarcomere disassembly and early embryonic lethality.18 Remarkably, knockout of cTnI in murine embryos has no impact on health before postnatal working day fifteen, attributable to ssTnI compensating for the lack of cTnI.
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39 observed the concentration of cTnT peaking simultaneously as CK-MB (localized in the cytosol), and considering the fact that the discharge profile of cTnT was biphasic, these observations can not be accounted for by infarct-zone clearance/washout on your own.
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